Make sure to zero your weapon with the can on it and know where POI is if you have to remove it. They often change more than you would think. Use your hunting ammo also to zero, trust me on this one.
There was a 3" shift in my POI with 130 gr Hog Hammers/Barnes TSX when suppressed. I've made the necessary adjustments and am ready to get my first suppressed kill with it.