22lr can be leathal at 450 yr

The vast majority of the time, you die from a gun shot by bleeding to death. If you sever the brain stem or the spinal cord between the brain stem and the heart, you die from heart failure.

Every other scenario is bleeding to death.

SO, bleeding to death is what makes bullets lethal. A bigger bullet makes a bigger hole and does more damage to the tissue and has more opportunity to cause bleeding.

I would say that SHOCK is the leading cause, then bleeding out.
You can stop bleeding in most cases but most people cant handle the shock, feel it coming or know how to fight it off.

But I've been wrong 3 times today already, so....
 
How much energy does a 40 grain rimfire round have left at 400 yards? Under 50 lbs? How much damage is that going to do to anything of any size?

47.1 ft lbs @ 400
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