Great thread. It seems like you could make an airlock with the same idea as a water pipe. Just put your tubing in the wine bottle on one end and the other end into a glass if water about a 1/2". As it builds pressure it will vent some bubbles but there would never be a vacuum in the bottle to draw the water up the tube and into the wine bottle (or 2litter bottle)
let us know how it tastes
let us know how it tastes