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If it’s life or death I’d have to try 1 good shot with a centerfire with my weak hand. But I obviously don’t know how much pain your in. However if 22 Is all I got I’d say 22a with stingers in it.
Good luck with the shoulder surgery! I am having a total shoulder replacement in 2 weeks. The same thoughts crossed my mind about defensive options while recovering.
My anecdote cancels yours out...The old 22 for self-defense thread, no matter what you do it will always come back...
If you're set on using 22 drill a small hole in the projectile and put a high explosive in it and always practice reloading magazines, lots of magazines...
There was a young lady not too long ago on this side of town who kept a 22 next to her bad I believe it had 10 Rounds. Anyway, she was attacked one night and while the rapist was busy abusing her he was yelling for money as well. She told him she had hundreds of dollars she would give everything to him if he would just stop.
So he got up she reached in the dresser drawer pulled out the 22 unloaded all 10 Rounds into him.
As he was running out the door with her in Pursuit she managed to grab the 12 gauge behind the front door and drop him at about 20 feet away.
The moral of the story is if you're going to use a 22 for self-defense make sure you have a higher caliber back up...
If you get the PMR 30 take multiple rounds out and do test runs on which will preform as it should..Mine had several failure to feed and extract problems. pulled the slide and polished the feed ramp and used dry graphite to lube the spring in the mags..Get yourself a PMR 30 if you can... 30 rounds of 22 magnum is no joke and the gun is light and very shootable, plus they are reasonably priced now that supply has caught up with demand.
That being said, if someone does break in while you are still convalescing, I think the adrenaline will more than make up for any physical pain if you simply use your regular carry gun.