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Because it's a rimless cartridge and there's no demand for such...
RNC, I have never seen a .45acp lever rifle. But, I am sure somewhere, someone has converted a lever action rifle to .45acp. I guess you could start with a .44mag, bore out the barrel, and then..........wait, why do that? I would rather have a rifle in .44mag!
Nope, never seen one, but that does not they don't or haven't existed in some form or another.