A modern python if built to the same standards of the original python would retail for over 4 grand. If anything it will increase the value of the originals...
I've heard at least two different interviews with Colt execs say the exact same thing. The snake guns required a ton of hand fitting, and Colt got rid of a lot of the tooling needed to make them after they stopped production. They both estimated that the start up costs alone would put a 'new' Python at $5K or more.